Quantitative Proteomics Analysis of the cAMP/Protein Kinase A Signaling Pathway
نویسندگان
چکیده
منابع مشابه
Quantitative Proteomics Analysis of the cAMP/Protein Kinase A Signaling Pathway
To define the proteins whose expression is regulated by cAMP and protein kinase A (PKA), we used a quantitative proteomics approach in studies of wild-type (WT) and kin- (PKA-null) S49 murine T lymphoma cells. We also compared the impact of endogenous increases in the level of cAMP [by forskolin (Fsk) and the phosphodiesterase inhibitor isobutylmethylxanthine (IBMX)] or by a cAMP analogue (8-CP...
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ژورنال
عنوان ژورنال: Biochemistry
سال: 2012
ISSN: 0006-2960,1520-4995
DOI: 10.1021/bi301282k